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101年度
Endogenous granulocyte colony-stimulating factor:A biomarker in acute ischemic stroke |
| 作 者： |
尤世杰
Kuo CL
Huang CS
Chang CS
Wu SL
Su SL
Liu CS
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科別： |
神經內科 |
| 發表雜誌期刊名稱： |
Biomarkers. |
發表之雜誌期刊
時間或卷期： |
2012 Jun;17(4):319-24. |
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摘要： |
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| Granulocyte colony-stimulating factor (G-CSF) may protect ischemic brain injury either in animal or human. No studies have reported that endogenous G-CSF (enG-CSF) level is related to the severity of ischemic stroke. This study was designed to assess the severity of ischemic patients correlated with the alteration of enG-CSF on the 1st day after an ischemic event. Patient's plasma enG-CSF and scoring of National Institute of Health Stroke Scale were measured on the 1st day after ischemic stroke. The acute ischemic stroke could significantly induce enG-GCF secretion as compared with healthy control group (16.77 vs. 22.86 μg/L, p = 0.001). Elevated enG-CSF concentration was positively correlated with the severity of stroke patients on day 1 after the event (p = 0.006; Spearman correlation coefficient = 0.268). The enG-CSF is a good biomarker for prediction of severity of acute ischemic stroke |
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最後修改時間：2012/8/23 上午 11:07:00 |
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